AceProbe collaborates with AIIMS to deliver data on cardiovascular events

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All India Institute of Medical Sciences and AceProbe have entered into a collboration to deliver data on the Indian population for certain cardiovascular events which shall help deliver information regarding clinical evidence for improved patient outcomes.

ACS represent a spectrum of events ranging from unstable angina (UA) and non–ST-segment elevation myocardial infarction (NSTEMI) to ST-segment elevation myocardial infarction (STEMI). ACS events are frequently the consequence of thrombotic occlusion of a coronary artery. Intervention at this point in the CVD continuum clearly interrupts disease progression by preventing cardiac muscle death, decreasing the risk of a recurrent ischemic event, slowing progression to heart failure, and reducing mortality. Patients presenting with an ACS must receive prompt treatment to prevent ischemic complications; optimal management includes anti-ischemic therapy (eg, supplemental oxygen, nitroglycerin, and β-blocker), antiplatelet agents (eg, aspirin, clopidogrel, or platelet glycoprotein [GP] IIb/IIIa inhibitor), antithrombotic therapy (unfractionated heparin, low-molecular-weight heparin [LMWH]), and the use of invasive reperfusion procedures (ie, percutaneous coronary intervention [PCI] or coronary artery bypass grafting [CABG]). For STEMI patients, optimal therapy also includes fibrinolytic agents to restore blood flow in the occluded coronary artery.

GenoMeet 2012

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AceProbe - Dr. Charles R Cantor- Sequenom -presents at the Genomeet 2012- Genomics for Next Decade.

Dr Charles Cantor presents at the Genomeet 2012 - an event opened by IGIB ( Institute of Genomics & Integrative Biology), his talk titled, " Prospects for non-invasive personalized genomics. 

Charles Cantor
Boston University

Nucleic acids of all sorts can be found in a range of easily accessible clinical samples such as buccal swabs, hair follicles, blood, urine, feces, sperm, and samples that can be obtaining by minimally invasive procedures such as fine needle biopsies, and lavage of various body cavities. For germ line analysis most of these sites are equivalent. For the analysis of somatic mutations, transcripts, epigenetics and nucleic acids arising from specific compartments, only certain samples will be useful. Non-invasive prenatal diagnosis by examining DNA spilled into the maternal circulation by fetal and placental apoptosis is well established, and for aneuploidies and a few other traits it is now commercially available, It is only a matter of time before similar diagnostic tools mature for tumor-specific nucleic acids spilled into the circulation my cancer cell apoptosis. How broadly this paradigm can be extended to other clinical situations will be a subject for intense research in the near future. From p[re-natal studies it is known that the entire fetal genome is represented in the mother’s blood. The rate of DNA or RNA turnover is rapid so that a maternal plasma analysis represents a snapshot of the current status of the fetus. The major technical challenge is accurately assessing trace amounts of fetal or tumor-specific nucleic acids in the presence of a large excess of similar or identical host species. Scalable techniques for known markers allow routine detection at 0.2$ abundance providing that the total number of molecules is large enough to avoid stochastic noise.

AceProbe decodes the Meat Adulteration Solution

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AceProbe Announces the completion and securing the Assays that are suitable for detection of adultration of varied animal species.