DNA Synthesis

Since 1999, BioAutomation has served the biotechnology industry with automation solutions to assist in research and development.

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Synthesizers

BioAutomation offers a full line of DNA / RNA oligonucleotide synthesizers as well as custom models to meet our customer’s needs. Our synthesizers are as efficient and as fast as any oligonucleotide synthesizers on the market. With unparalleled throughput, ease of use, and world wide service, the MerMade line of synthesizers is the clear choice for any lab looking for an Oligonucleotide synthesizer. All MerMades come equipped with 10 amidite ports (more available upon request) and a dedicated Thio position.
All MerMades also have the following features:
    • The easiest to use and most flexible software available
    • Fast cycle times
    • Low reagent consumption
    • High reliability
    • Ability to synthesize long oligos (>100bp w/ 99% coupling efficiency)
    • Low operational cost per oligo produced
    • Can be configured to accept reagents from any bottle or keg
    • Unsurpassed worldwide service
    • Included Customer-site installation and 1yr parts and labor
    • Comes complete with Dell Computer workstation with all software loaded and pre-configured with protocols for synthesizing DNA and RNA at multiple scales.
The MerMade’s simple and robust design allows easy maintenance and service. Built from commercially available parts, BioAutomation unlike our competition, does not lock you into expensive service contacts by not selling key parts. This also guarantees that if we ever discontinue a model you will not be stuck with an instrument for which you can’t get parts. To see a full comparison of the MerMades to some other synthesizers
Let BioAutomation Run your Sequences!
BioAutomation will run up to 12 DNA oligos at the 50nmole scale on the MerMade of your choice and send you the crude material for analysis. You may inquire about tests for modified oligos as well as larger scales.

STANDARD FEATURES
  • 10 Amidite Ports
  • Scales range from 20nanomole to 5micromole
  • Flexible and easy to use software that runs on Windows 7
  • Run Logging
  • Mixed backbone capability (phosphorothioate and phosphodiester)
  • Dell PC & monitor included with extended warranty
  • Pre-loaded with standard protocols
  • Cleavage apparatus included
OPTIONAL FEATURES
  • Trityl Monitoring
  • UPS back up to allow synthesis recovery in the event of power loss
  • Multiple reagent cap adapters
  • Bar code reader
  • Custom integration of software with in house LIMS

STANDARD FEATURES
  • 10 to 20 Amidite Ports
  • Scales range per column from 20nanomole to over 200micromole
  • Flexible and easy to use software that runs on Windows 7
  • Run Logging
  • Mixed backbone capability (phosphorothioate and phosphodiester)
  • Dell PC & monitor included with extended warranty
  • Pre-loaded with standard protocols
  • Cleavage apparatus included
OPTIONAL FEATURES
  • Low dead volume bottle mount for expensive modifiers
  • 6 to 12 columns
  • Up to 20 amidite ports (inquire if more are needed)
  • Trityl Monitoring
  • UPS back up to allow synthesis recovery in the event of power loss
  • Multiple reagent cap adapters
  • Bar code reader
  • Custom integration of software with in house LIMS

The MerMade 192E Oligonucleotide synthesizer is designed to synthesize DNA, RNA & LNA oligonucleotides in a column format using standard or modified chemistries. The 192E can synthesize 192 oligos in less than 3 hours, producing a very high quality product with very minimal reagent usage. The 192E is ideally suited for those who need a fast synthesizer that is capable of producing high quality oligos that do not require extensive modifications.  Please contact our Sales department for pricing (info@aceprobe.com).


STANDARD FEATURES
  • 8 Amidite Ports
  • Scales range from 20nanomole to 5micromole
  • Fully featured API for remote monitoring and control
  • Flexible and easy to use software that runs on Windows 7
  • Run Logging
  • Mixed backbone capability (phosphorothioate and phosphodiester)
  • Dell PC & monitor included with extended warranty
  • Pre-loaded with standard protocols
  • Cleavage apparatus included
OPTIONAL FEATURES
  • UPS power back up allows synthesis recovery in the event of power loss
  • Multiple reagent cap adapters
  • Bar code reader
  • Argon pressure sensor
  • Custom integration of software with in house LIMS

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